We present lattice QCD results of baryon-baryon potentials in S=-3
sector, i.e., XiSigma (I=3/2) potentials and XiLambda-XiSigma coupled
channel potentials (I=1/2) by using the 2+1 flavor gauge
configurations with almost the physical quark masses generated on 96^4
lattice with 1/a = 2.3 GeV and L = 96a = 8.1 fm where m_pi = 146 MeV
and m_K = 525 MeV. These potentials are obtained based on the
time-dependent HAL QCD method with a non-relativistic approximation.
Qualitative behaviors of the results are found to be consistent with
those in the flavor SU(3) limit.