Recent discoveries in astrophysics of cosmic rays (CR) and $\gamma$-ray astronomy demand more accurate and reliable CR propagation code. Having 21 years of development behind it, the GALPROP model has become a de-facto standard in astrophysics of CR, diffuse $\gamma$-rays, and searches of new physics. The GALPROP project is devoted to the development of a self-consistent model for CR propagation in the Galaxy and associated diffuse emissions (radio, microwave, X-rays, $\gamma$-rays). The project stimulated independent studies of the interstellar radiation field (ISRF), distribution of the interstellar gas (H$_2$, H I, H II), synchrotron emission and the Galactic magnetic field, and a new study of the isotopic production cross sections. These studies provide necessary and unique input datasets for the GALPROP model. The code is optimized and parallelized and accessible as a standalone executable or library that can be linked to other codes enabling many other studies, such as Markov Chain Monte Carlo, MultiNest, SuperBayeS, and DarkSUSY. The new version of the code has many updates that improve its accuracy and capabilities. As always, the latest release of the code is available through the WebRun, a service to the scientific community enabling easy use of the GALPROP code via web browsers.