The LHCb detector is a single-arm forward spectrometer, which measures proton-proton interactions at the LHC. For Run II (2015-2018) LHCb has introduced a novel real-time detector alignment and calibration strategy. Data collected at the start of the fill are processed and used to update the alignment, while the calibration constants are evaluated for each run. In this document an overview of the real-time alignment and calibration strategy is presented, followed by the discussion of the latest developments.