Most of the radio-loud narrow-line Seyfert 1 (NLS1) galaxies resemble compact steep-spectrum sources. However, the extremely radio-loud ones show blazar-like characteristics, like flat radio spectra, compact radio cores, substantial variability and high brightness temperatures. These objects are thought to be similar to blazars as they possess relativistic jets seen at small angle to the line of sight. This claim has been further supported by the Fermi satellite discovery of gamma-ray emission from a handful of these sources. Using the Wide-Field Infrared Survey Explorer (WISE) data, we analyzed the mid-infrared variability characteristics of $42$ radio-loud NLS1 at $3.4$ and $4.6\,\mu$m. We found that $27$ out of the studied $42$ sources showed variability in at least one of the two infrared bands. In some cases, significant changes in the infrared colors can alter the location of the source in the WISE color-color diagram which might lead to different classification. More than $60$% of the variable sources also showed variability within a $1-1.5$ day interval. Such short time scales argue for a compact emission region like those associated with the jets. This connection is further strengthened by the fact that the brightest $\gamma$-ray emitters of the sample ($6$ sources), all showed short time scale infrared variability.