The Cosmic Ray Energetic And Mass for the International Space Station (ISS-CREAM) experiment is designed for precision measurements of energy spectra and elemental composition of cosmic rays. It was launched and installed on the ISS in August 2017. The Silicon Charge Detector (SCD), placed at the top of the ISS-CREAM payload, consists of 4 layers with a total of 10,752 silicon pixels which have 1.37 × 1.57 cm^2 size each. Each layer is arranged in such a fashion that its active detection area of 78 × 74 cm^2 is free of any dead area. The SCD 4-layer conﬁguration was chosen to achieve the best precision in measuring the charge of cosmic rays from proton to iron nuclei with a charge resolution of 0.1 − 0.3e. We will present its on-orbit performance and operation status on the ISS since the launch.