Dipole operators encode a rich variety of phenomena, such as radiative decays and electric dipole moments in both quark and lepton sectors, which probe physics beyond the Standard Model up to very high energy scales. Through renormalization, non-dipole operators mix into dipole ones, thus possibly generating observable effects that can be investigated by those same phenomena. I discuss the calculation of this mixing in cases where the leading order effect happens at two-loops (i.e., when one-loop effects vanish), and the phenomenological consequences for flavor and $ \mathbf{CP} $ violation coming from New Physics described by operators of dimension six.