The current mandate of the LHC experiments is to precisely determine the properties of the Higgs boson, one of the major interests being the top-Yukawa coupling ($y_t$) measurement. The Run 2 data have provided evidence of $\mathrm{t\bar{t}H}$ production at the LHC which is sensitive to $y_t^2$ at the tree level. In contrast, the $\mathrm{tHq}$ process provides information on the relative sign of $y_t$ with respect to the Higgs to vector boson coupling ($g_{HVV}$). According to the Standard Model (SM), the cross section of the $\mathrm{tHq}$ process is very low even at 13 TeV centre of mass energy ($\sqrt{s}$). However, in case of anomalous Higgs couplings the cross section may be enhanced and be detected with a limited amount of integrated luminosity ($L$). Results are presented from Run 2 measurements of the $\mathrm{tHq}$ process using LHC data collected by the CMS experiment. Future prospects of the search are discussed in the context of High Luminosity LHC (HL-LHC).