During the outbreak of the Covid-19 epidemic, many countries took strict measures of prevention, including city lockdowns, production, school shutdowns, and home quarantine, to prevent further spread of the pandemic. Relevant actions have affected people's daily routines and life patterns, even changed the original lifestyle. Especially for youngsters, their diversified lifestyle is significantly impacted. Related studies show that abnormal changes in daily life patterns or bad habits change the lifestyle and lead to the emergence of a sub-health state. Therefore, the primary purposes of this study are 1. to investigate the differences in lifestyle among young generation before and during the epidemic; 2. to further analyze the changes and the factors that may affect their health. in order to increase people's interest in the research and enhance the participation of young generation, this study introduces the method of "Life Stripe Project" established by Japanese designers. Based on this model, the questionnaire of daily life patterns was derived online, where data of daily life activities of college students in Taiwan and mainland China were collected through an online survey. At the same time, six factors of health-promoting lifestyle theory have been introduced to analyze the factors affecting the lifestyle change before and during the epidemic, and to find out the reasons resulting in the sub-health state, to guide the young generation to deal with the possible continuation of the epidemic situation. Proper adjustment and plans for their daily life activities will help to enhance their awareness of health-promoting life in the future.