The Cosmic Ray Energetics And Mass for the International Space Station (ISS-CREAM) experiment successfully recorded data for 539 days from Aug. 2017 to Feb. 2019. The ISS-CREAM instrument consists of a Silicon Charge Detector (SCD), carbon targets, a calorimeter (CAL), a top counting detector (TCD), a bottom counting detector (BCD), and a boronated scintillator detector (BSD). In this analysis, the SCD was used for the charge measurements. It comprises four layers, and each SCD layer is finely segmented with 2,688 silicon pixels to minimize charge misidentification due to the backscattered particles. The CAL was used for the energy measurements. It comprises 20 layers of tungsten/scintillating fibers. Each tungsten/scintillating-fiber layer consists of a 50 cm × 50 cm × 3.5 mm tungsten plate, followed by a layer of fifty 1 cm-wide 50 cm-long scintillating-fiber ribbons. The CAL also provides the incident cosmic-ray track and the high-energy trigger. For the low-energy trigger, the TCD and BCD were used. In this paper, we present the proton spectrum from the ISS-CREAM experiment in the energy range of 1.6 - 655 TeV and the preliminary helium spectrum in the energy range of 2.7 TeV - 1.1 PeV