The Zirè experiment is part of the NUSES (NeUtrino and Seismic Electromagnetic Signals) space mission, proposed by the Gran Sasso Science Institute (GSSI) in collaboration with the Istituto Nazionale di Fisica Nucleare (INFN) and by Thales Alenia Space Italy (TAS-I), involving many Institutes and Universities from Europe and abroad. Zirè will perform measurements of electrons, protons and light nuclei from few up to hundreds of MeVs, for the study of low energy CRs, space weather phenomena and possible Magnetosphere-Litosphere-Ionosphere Coupling (MILC) signals. A further goal of the experiment is to test new tools for the detection of photons in the energy range 0.1 MeV - 50 MeV, allowing the investigation of transient phenomena and steady gamma sources. Zirè will also test an innovative feature for space-based particle detectors, exploiting a full Silicon Photo Multiplier (SiPM) technology for the readout system. In this work, a general overview of the design activities, together with the scientific goals and the development status of the Zirè payload will be presented.