This document presents the measurements of the Higgs boson (H) couplings with the data from proton-proton collisions at a center-of-mass energy of 13 TeV collected by the CMS experiment. After more than ten years since the H discovery, one of the main goals of the LHC physics program is the characterization of this particle, which includes measurements of its mass, decay width, and couplings. In order to perform an extensive test of the standard model (SM) predictions, the measurements of the H cross sections and branching ratios in the most sensitive production and decay channels are statistically combined. The measurements are interpreted in terms of deviations of H couplings to fermions and vector bosons from the SM. No significant deviations are observed. The uncertainty on most of the couplings is better than $10\% $. Constraints on the H boson trilinear self-coupling constant ($\lambda$) are also extracted from the combined H cross section and branching ratio measurements. The H production cross sections and decay branching ratios depend on $\lambda$ because of electroweak corrections at the next-to-leading order. The results are found consistent with the SM and the constraints on $\lambda$ are similar to the ones extracted from the searches for the H pair production.