We extend the QCD Parton Model analysis by employing a factorized nuclear structure model that explicitly accounts for both individual nucleons and correlated nucleon pairs. This novel framework establishes a paradigm that directly links the nuclear physics description of matter (in terms of protons and neutrons) to the particle physics schema (in terms of quarks and gluons). Our analysis of high-energy data from lepton Deep-Inelastic Scattering, Drell-Yan, and W/Z production simultaneously extracts the universal effective distribution of quarks and gluons inside correlated nucleon pairs, and their nucleus-specific fractions. The successful extraction of these universal distributions marks a significant advance in our understanding of nuclear structure, as it directly connects nucleon-level and parton-level quantities.