In this proceeding, we present the mixed QCD-EW two-loop virtual corrections for the charged current Drell-Yan production. The presence of one additional mass compare to the neutral current case makes the computation of the two-loop amplitudes extremely challenging, specially the two-loop Feynman integrals. Our approach to evaluate the relevant two-loop Feynman integrals using semi-analytical method, allows us to obtain the renormalized two-loop amplitudes. We perform the subtraction of the universal infrared singularities mostly analytically and evaluate the hard function numerically as a grid.