The Glashow resonance, expected to occur in the interaction of high energy electron antineutrinos with electrons in the Earth’s matter, was postulated in the late 1960s but still remains unobserved. The biggest challenge for the observation of this phenomena is reaching the capability to detect neutrinos with an enormous energy (about 6.3 PeV). The KM3NeT-ARCA (Astroparticle Research with Cosmics in the Abyss) detector, currently under construction in the Mediterranean deep sea, is optimized to observe very high energy neutrinos of astrophysical origin. In this work the sensitivity of the KM3NeT-ARCA for the Glashow resonance detection is reported. Preliminary results show that the discovery of the Glashow resonance can be possible with KM3NeTARCA after 15 years of operation. However, the final prediction depends very strongly on the astrophysical neutrino flux model, which is still not well constrained.