The minimal realistic SO(10) model with the adjoint representation causing the GUT symmetry breaking is an appealing candidate for a realistic Grand Unified Theory. Moreover, the model allows one to make significant improvement in the proton lifetime error estimates due to the suppression of the potential gravitational effects influencing the GUT scale physics. We performed a comprehensive numerical study of the proton decay width including one-loop quantum effects mandatory in the physically relevant scenarios. The model’s study was also extended by improved perturbativity constraints. We present a thorough discussion of various consistency constraints that were used to asses theory's viability.