Mini-EUSO (Multiwavelength Imaging New Instrument for the Extreme Universe Space Observatory) is a telescope observing the Earth from the International Space Station since 2019. The instrument employs a Fresnel-lens optical system and a focal surface composed of 36 Multi-Anode Photomultiplier tubes, 64 channels each, for a total of 2304 channels with single photon counting sensitivity.
Mini-EUSO observes the night-time Earth in the near UV range (predominantly between 290 - 430~nm) with a spatial resolution of about 6.3~km (full field of view equal to 44$^{\circ}$) and a temporal resolution of 2.5~$\mu$s, observing our planet through a nadir-facing UV-transparent window located in the Russian Zvezda module.
The detector can thus acquire triggered transient phenomena with a sampling rate of 2.5 $\mu$s and 320~$\mu$s, as well as perform continuous acquisition at 40.96~ms scale.
Among the scientific objectives addressed by the mission is the observation of meteors (at the 40.96 ms time frame), the search for interstellar meteors and amongst them, the search for strange quark matter (SQM), appearing as anomalous (long track and fast-moving) meteor events.
In this paper we discuss the observational capabilities for Mini-EUSO and the limits it will pose to SQM and other Macro-like particles.