In this work we present preliminary results on the nucleon axial and tensor charges, the quark momentum fraction and the first moment of the helicity distribution. The simulations have been performed using two $N_f{=}2$ and $N_f{=}2{+}1{+}1$ ensembles. Both ensembles have a twisted mass action with a clover term with the quark masses fixed at their physical values (physical point) and volumes of $64^3{\times}128$. The extracted quantities are compared with results from an existing $N_f{=}2$ ($48^3{\times}96$) ensemble. This comparison allows one to address volume and quenching effects.