We review the most precise tests of the CKM model of flavour physics performed by the LHCb collaboration during 2021.
These include world best measurements of both time-dependent and time-independent $CP$ violation in charm decays, the first observation of a nonzero mass difference of the neutral charm-meson eigenstates, and the most precise determination to date of the mass difference between the $B^0_s$ eigenstates.
A new simultaneous combination of measurements of the CKM angle $\gamma$ and of charm decays allows to improve the precision on the decay-width difference of the neutral charm-meson eigenstates by a factor of 2 with respect to the combination of charm results only.