Gamma rays constitute a privileged point of view for the study of the extreme Universe. Unlike charged cosmic rays, which are thought to have a common origin, gamma rays are not deflected by galactic and intergalactic magnetic fields. This offers the opportunity to unveil the most powerful particle accelerators, still largely unknown, once modifications in the gamma-ray flux, arrival time, and angular distribution due to propagation effects are considered.

Gamma ray telescopes include a large variety of instruments, both satellite-born and ground-based, which cover a broad energy range. These lecture notes provide an overview of the detection techniques for gamma-ray astronomy. A detailed description of the gamma-ray propagation effects in the galactic and extragalactic scenarios is also provided.