In this work we consider the effects of Lorentz Invariance Violation over the observed flux of very high-energy neutrinos. For that, we study the neutrino propagation in a Modified Dispersion Relation scenario with a superluminal velocity. This makes the neutrino unstable and causes a cut-off in the flux of detected neutrinos. Using simple models, one can approximate the location of the cut-off as functions of the parameters of new physics and the closest source.